BRD4 anticorps (C-Term)

N° du produit ABIN6242208

Détail du produit anti-BRD4 anticorps

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Épitope: AA 1313-1342, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRD4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1313~1342 amino acids from the C-terminal region of human BRD4.

Clone: RB3422

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-BRD4 (ABIN6242208)

Yamada, Honma, Mochizuki, Goda: "BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver." dans: Metabolism: clinical and experimental, Vol. 65, Issue 10, pp. 1478-88, (2017) (PubMed).

Sénéchal, Poirier, Coulombe, Laimins, Archambault: "Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4." dans: Virology, Vol. 358, Issue 1, pp. 10-7, (2007) (PubMed).

Kurg, Tekkel, Abroi, Ustav: "Characterization of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers." dans: Journal of virology, Vol. 80, Issue 22, pp. 11218-25, (2006) (PubMed).

Kurg, Sild, Ilves, Sepp, Ustav: "Association of bovine papillomavirus E2 protein with nuclear structures in vivo." dans: Journal of virology, Vol. 79, Issue 16, pp. 10528-39, (2005) (PubMed).

Détails sur BRD4

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Autre désignation: BRD4 (BRD4 Produits)

Synonymes: anticorps brd4-b, anticorps BRD4, anticorps fb18g03, anticorps wu:fb18g03, anticorps CAP, anticorps HUNK1, anticorps HUNKI, anticorps MCAP, anticorps Brd5, anticorps WI-11513, anticorps bromodomain containing 4 L homeolog, anticorps bromodomain containing 4, anticorps bromodomain-containing protein 4, anticorps brd4.L, anticorps BRD4, anticorps brd4, anticorps LOC100409351, anticorps Brd4

Sujet: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people.

Poids moléculaire: 152219

NCBI Accession: NP_055114, NP_490597

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome