FOXN4 anticorps (C-Term)

N° du produit ABIN6242346

Détail du produit anti-FOXN4 anticorps

Antigène: FOXN4 (Forkhead Box N4 (FOXN4))

Épitope: AA 436-470, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXN4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FOXN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 436-470 amino acids from the C-terminal region of human FOXN4.

Clone: RB52411

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur FOXN4

Antigène: FOXN4 (Forkhead Box N4 (FOXN4))

Autre désignation: FOXN4 (FOXN4 Produits)

Synonymes: anticorps whn, anticorps whna, anticorps forkhead box N4, anticorps forkhead box N4 S homeolog, anticorps FOXN4, anticorps foxn4, anticorps Foxn4, anticorps foxn4.S

Sujet: Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

Poids moléculaire: 55215

UniProt: Q96NZ1