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MBD2 anticorps (AA 10-228)

MBD2 Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 1812CT625-9-45 unconjugated
N° du produit ABIN6242434
  • Antigène Voir toutes MBD2 Anticorps
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Épitope
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-228
    Reactivité
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 1
    • 1
    Souris
    Clonalité
    • 45
    • 2
    Monoclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MBD2 est non-conjugé
    Application
    • 40
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogène
    This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
    Clone
    1812CT625-9-45
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MBD2 Anticorps primaire
  • Indications d'application
    WB: 1:2000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Autre désignation
    MBD2 (MBD2 Produits)
    Synonymes
    anticorps MBD2, anticorps DMTase, anticorps NY-CO-41, anticorps MBD2a, anticorps wu:fa97f06, anticorps zgc:111862, anticorps methyl-CpG binding domain protein 2, anticorps methyl-CpG binding domain protein 2 S homeolog, anticorps MBD2, anticorps Mbd2, anticorps mbd2, anticorps mbd2.S
    Sujet
    Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
    Poids moléculaire
    43255
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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