Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PDCD6 anticorps (AA 103-137)

PDCD6 Reactivité: Souris WB Hôte: Lapin Polyclonal RB49787 unconjugated
N° du produit ABIN6242573
  • Antigène Voir toutes PDCD6 Anticorps
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    Épitope
    • 14
    • 7
    • 6
    • 1
    • 1
    • 1
    AA 103-137
    Reactivité
    • 48
    • 11
    • 10
    Souris
    Hôte
    • 46
    • 2
    Lapin
    Clonalité
    • 46
    • 2
    Polyclonal
    Conjugué
    • 15
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PDCD6 est non-conjugé
    Application
    • 30
    • 27
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6.
    Clone
    RB49787
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDCD6 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    Autre désignation
    PDCD6 (PDCD6 Produits)
    Synonymes
    anticorps pdcd6, anticorps MGC52821, anticorps MGC132114, anticorps zgc:63952, anticorps PDCD6, anticorps ALG-2, anticorps PEF1B, anticorps AV299538, anticorps Alg2, anticorps MA-3, anticorps PS2, anticorps alg-2, anticorps programmed cell death 6 L homeolog, anticorps programmed cell death 6, anticorps pdcd6.L, anticorps pdcd6, anticorps PDCD6, anticorps Pdcd6
    Sujet
    Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
    Poids moléculaire
    21868
    UniProt
    O75340
    Pathways
    Positive Regulation of Endopeptidase Activity
Vous êtes ici:
Support technique