SRY anticorps (AA 81-112)

N° du produit ABIN6242645

Détail du produit anti-SRY anticorps

Antigène: SRY (Sex Determining Region Y (SRY))

Épitope: AA 81-112

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRY est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SRY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-112 amino acids from the Central region of human SRY.

Clone: RB53826

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur SRY

Antigène: SRY (Sex Determining Region Y (SRY))

Autre désignation: SRY (SRY Produits)

Synonymes: anticorps SRXX1, anticorps SRXY1, anticorps TDF, anticorps TDY, anticorps SRYGENE, anticorps Sry1, anticorps Sry3BI, anticorps Tdf, anticorps Tdy, anticorps SRY, anticorps sex determining region Y, anticorps sex determining region of Chr Y, anticorps SRY, anticorps Sry

Sujet: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Poids moléculaire: 23884

UniProt: Q05066