MLL3 anticorps (C-Term)

N° du produit ABIN6242808

Détail du produit anti-MLL3 anticorps

Antigène: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Épitope: AA 3784-3818, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3784-3818 amino acids from the C-terminal region of human MLL3.

Clone: RB52486

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur MLL3

Antigène: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Autre désignation: MLL3 (KMT2C Produits)

Synonymes: anticorps HALR, anticorps MLL3, anticorps E330008K23Rik, anticorps Mll3, anticorps mKIAA1506, anticorps lysine methyltransferase 2C, anticorps lysine (K)-specific methyltransferase 2C, anticorps KMT2C, anticorps Kmt2c

Sujet: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Poids moléculaire: 541370

UniProt: Q8NEZ4

Pathways: L'effet Warburg