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Sonic Hedgehog anticorps (C-Term)

Name: Sonic Hedgehog anticorps (C-Term)
SKU: ABIN6242829
Price: 445.5 EUR
Availability: InStock

SHH Reactivité: Souris WB, FACS Hôte: Lapin Polyclonal RB51214 unconjugated

Western blot analysis of lysate from mouse liver tissue lysate, using Shh Antibody (C-term) (ABIN6242829 and ABIN6577864). (Sonic Hedgehog anticorps (C-Term))

Flow cytometric analysis of Hela cells using (Mouse) Shh Antibody (C-term)(green, Cat(ABIN6242829 and ABIN6577864)) compared to an isotype control of rabbit IgG(blue). (Sonic Hedgehog anticorps (C-Term))

FACS

2 images

N° du produit ABIN6242829

Fiche de données

Antigène Voir toutes Sonic Hedgehog (SHH) Anticorps

Sonic Hedgehog (SHH)
Épitope
15

12

9

5

4

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 397-431, C-Term
Reactivité
66

49

37

17

10

6

6

5

2

2

2

1

1

1

1

1

1

1
Souris
Hôte
72

12

8

1

1
Lapin
Anticorps secondaires appropriés
Clonalité
67

27
Polyclonal
Conjugué
51

8

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp Sonic Hedgehog est non-conjugé
Application
68

28

23

14

13

11

9

6

6

6

5

4

3

1
Western Blotting (WB), Flow Cytometry (FACS)

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This Mouse Shh antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of mouse Shh.

Clone

RB51214

Isotype

Ig Fraction

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anti-Sonic Hedgehog (SHH) (C-Term) antibody
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SHH Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

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SHH Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal D6 unconjugated

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SHH Reactivité: Humain, Souris, Rat WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB52387 unconjugated

anti-Sonic Hedgehog (SHH) (AA 24-197) antibody
SHH Reactivité: Humain, Rat, Chien, Singe WB, IF Hôte: Souris Monoclonal 10H6 unconjugated

anti-Sonic Hedgehog (SHH) (AA 237-399) antibody
SHH Reactivité: Rat WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated

anti-Sonic Hedgehog (SHH) (AA 203-218), (N-Term) antibody
SHH Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:1000. FC: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Date de péremption

6 months
Antigène

Sonic Hedgehog (SHH)

Autre désignation

Shh (SHH Produits)

Synonymes

anticorps HHG1, anticorps HLP3, anticorps HPE3, anticorps MCOPCB5, anticorps SMMCI, anticorps TPT, anticorps TPTPS, anticorps 9530036O11Rik, anticorps Dsh, anticorps Hhg1, anticorps Hx, anticorps Hxl3, anticorps M100081, anticorps fc83d08, anticorps shh, anticorps syu, anticorps vhh-1, anticorps vhh1, anticorps wu:fc83d08, anticorps Xhh, anticorps hedgehog, anticorps xshh, anticorps SHH, anticorps twh, anticorps twhh, anticorps sonic hedgehog, anticorps sonic hedgehog a, anticorps sonic hedgehog L homeolog, anticorps sonic hedgehog protein A, anticorps sonic hedgehog b, anticorps SHH, anticorps Shh, anticorps shha, anticorps shh.L, anticorps shh, anticorps shhb

Sujet

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).

Poids moléculaire

47773

UniProt

Q62226

Pathways

Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development