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DIAPH1 anticorps (N-Term)

DIAPH1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB30760 unconjugated
N° du produit ABIN6242839
  • Antigène Voir toutes DIAPH1 Anticorps
    DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
    Épitope
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-52, N-Term
    Reactivité
    • 33
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 5
    • 1
    Lapin
    Clonalité
    • 24
    • 10
    Polyclonal
    Conjugué
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DIAPH1 est non-conjugé
    Application
    • 20
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This DIAPH1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 18-52 amino acids from the N-terminal region of human DIAPH1.
    Clone
    RB30760
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DIAPH1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
    Autre désignation
    DIAPH1 (DIAPH1 Produits)
    Synonymes
    anticorps DIAPH1, anticorps dia1, anticorps drf1, anticorps dfna1, anticorps diap1, anticorps lfhl1, anticorps DIAPH2, anticorps Diap1, anticorps D18Wsu154e, anticorps Dia1, anticorps Diaph1, anticorps Drf1, anticorps mKIAA4062, anticorps p140mDia, anticorps DFNA1, anticorps DIA1, anticorps DRF1, anticorps LFHL1, anticorps hDIA1, anticorps diaphanous related formin 1, anticorps diaphanous related formin 2, anticorps diaphanous-related formin 1, anticorps protein diaphanous homolog 1, anticorps DIAPH1, anticorps diaph1, anticorps DIAPH2, anticorps Diaph1, anticorps LOC100457442
    Sujet
    Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration (By similarity). Has neurite outgrowth promoting activity (By similarity). In hear cells, it may play a role in the regulation of actin polymerization in hair cells. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
    Poids moléculaire
    141347
    UniProt
    O60610
    Pathways
    Sensory Perception of Sound
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