LECT1 anticorps (N-Term)

N° du produit ABIN6242902

Détail du produit anti-LECT1 anticorps

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Épitope: AA 1-30, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LECT1 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LECT1.

Clone: RB15072

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur LECT1

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Autre désignation: LECT1 (LECT1 Produits)

Synonymes: anticorps chm1, anticorps chm-i, anticorps bricd3, anticorps MGC53801, anticorps MGC82444, anticorps chondromodulin-I, anticorps Lect1, anticorps BRICD3, anticorps CHM-I, anticorps CHM1, anticorps MYETS1, anticorps Bricd3, anticorps ChM-I, anticorps Chm-1, anticorps chondromodulin L homeolog, anticorps leukocyte cell derived chemotaxin 1, anticorps chondromodulin, anticorps cnmd.L, anticorps lect1, anticorps CNMD, anticorps cnmd, anticorps Cnmd

Sujet: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.

Poids moléculaire: 37102

NCBI Accession: NP_001011705, NP_008946

UniProt: O75829