PPAP2A anticorps (C-Term)
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- Antigène Voir toutes PPAP2A Anticorps
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
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Épitope
- AA 270-304, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPAP2A est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This PPAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-304 amino acids from the C-terminal region of human PPAP2A.
- Clone
- RB51855
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
- Autre désignation
- PPAP2A (PPAP2A Produits)
- Synonymes
- anticorps PPAP2A, anticorps wun, anticorps LLP1a, anticorps LPP1, anticorps PAP-2a, anticorps PAP2, anticorps Hic53, anticorps Hpic53, anticorps LPP-1, anticorps mPAP, anticorps PAP2A, anticorps PAP2a2, anticorps phospholipid phosphatase 1, anticorps phosphatidic acid phosphatase type 2A, anticorps phospholipid phosphatase 1 L homeolog, anticorps PLPP1, anticorps plpp1, anticorps Ppap2a, anticorps plpp1.L, anticorps Plpp1
- Sujet
- Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.
- Poids moléculaire
- 32156
- UniProt
- O14494
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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