PPP6C anticorps (C-Term)

N° du produit ABIN6242920

Détail du produit anti-PPP6C anticorps

Antigène: PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

Épitope: AA 275-305, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP6C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-305 amino acids from the C-terminal region of human PPP6C.

Clone: RB5867

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PPP6C (ABIN6242920)

Williams, Filter, Blake-Hodek, Wadzinski, Fuda, Shalloway, Goldberg: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." dans: eLife, Vol. 3, pp. e01695, (2014) (PubMed).

Détails sur PPP6C

Antigène: PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

Autre désignation: PPP6C (PPP6C Produits)

Synonymes: anticorps PP6, anticorps PP6C, anticorps 2310003C10Rik, anticorps zgc:56227, anticorps ppp6c, anticorps PPP6C, anticorps pp6, anticorps MGC114734, anticorps DDBDRAFT_0168786, anticorps DDBDRAFT_0185210, anticorps DDB_0168786, anticorps DDB_0185210, anticorps CG12217, anticorps DmPpV-6A, anticorps Dmel\\CG12217, anticorps PPPV6A, anticorps PPV, anticorps PPV 6A, anticorps Ppv, anticorps dPP6, anticorps protein phosphatase 6 catalytic subunit, anticorps protein phosphatase 6, catalytic subunit, anticorps protein phosphatase 6, catalytic subunit L homeolog, anticorps serine/threonine-protein phosphatase 6 catalytic subunit, anticorps Protein phosphatase V, anticorps PPP6C, anticorps Ppp6c, anticorps ppp6c, anticorps ppp6c.L, anticorps ppp6C, anticorps PpV

Sujet: PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.

Poids moléculaire: 35144

NCBI Accession: NP_001116827, NP_001116841, NP_002712

UniProt: O00743