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PPP6C anticorps (C-Term)

PPP6C Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB5867 unconjugated
N° du produit ABIN6242920
  • Antigène Voir toutes PPP6C Anticorps
    PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
    Épitope
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 275-305, C-Term
    Reactivité
    • 43
    • 10
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 37
    • 3
    • 3
    Lapin
    Clonalité
    • 40
    • 3
    Polyclonal
    Conjugué
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    Cet anticorp PPP6C est non-conjugé
    Application
    • 35
    • 28
    • 9
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-305 amino acids from the C-terminal region of human PPP6C.
    Clone
    RB5867
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Williams, Filter, Blake-Hodek, Wadzinski, Fuda, Shalloway, Goldberg: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." dans: eLife, Vol. 3, pp. e01695, (2014) (PubMed).

  • Antigène
    PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
    Autre désignation
    PPP6C (PPP6C Produits)
    Synonymes
    anticorps PP6, anticorps PP6C, anticorps 2310003C10Rik, anticorps zgc:56227, anticorps ppp6c, anticorps PPP6C, anticorps pp6, anticorps MGC114734, anticorps DDBDRAFT_0168786, anticorps DDBDRAFT_0185210, anticorps DDB_0168786, anticorps DDB_0185210, anticorps CG12217, anticorps DmPpV-6A, anticorps Dmel\\CG12217, anticorps PPPV6A, anticorps PPV, anticorps PPV 6A, anticorps Ppv, anticorps dPP6, anticorps protein phosphatase 6 catalytic subunit, anticorps protein phosphatase 6, catalytic subunit, anticorps protein phosphatase 6, catalytic subunit L homeolog, anticorps serine/threonine-protein phosphatase 6 catalytic subunit, anticorps Protein phosphatase V, anticorps PPP6C, anticorps Ppp6c, anticorps ppp6c, anticorps ppp6c.L, anticorps ppp6C, anticorps PpV
    Sujet
    PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.
    Poids moléculaire
    35144
    NCBI Accession
    NP_001116827, NP_001116841, NP_002712
    UniProt
    O00743
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