NCOA2 anticorps (AA 1431-1462)

N° du produit ABIN6242925

Détail du produit anti-NCOA2 anticorps

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Épitope: AA 1431-1462

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NCOA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1431-1462 amino acids from human NCOA2.

Clone: RB53913

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur NCOA2

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Autre désignation: NCOA2 (NCOA2 Produits)

Synonymes: anticorps GRIP1, anticorps KAT13C, anticorps NCoA-2, anticorps SRC2, anticorps TIF2, anticorps bHLHe75, anticorps 9530095N19, anticorps D1Ertd433e, anticorps GRIP-1, anticorps Grip1, anticorps SRC-2, anticorps TIF-2, anticorps tif2, anticorps wu:fc41a10, anticorps wu:fe26a11, anticorps Tif2, anticorps NCOA2, anticorps XTIF2, anticorps bhlhe75, anticorps grip1, anticorps kat13c, anticorps src2, anticorps ncoa2-A, anticorps nuclear receptor coactivator 2, anticorps nuclear receptor coactivator 2 S homeolog, anticorps NCOA2, anticorps Ncoa2, anticorps ncoa2, anticorps LOC100089041, anticorps ncoa2.S

Sujet: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF- 2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK- ARNTL/BMAL1 heterodimer (By similarity).

Poids moléculaire: 159157

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling