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WNK1 anticorps (AA 1848-1882)

WNK1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB56242 unconjugated
N° du produit ABIN6242959
  • Antigène Voir toutes WNK1 Anticorps
    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
    Épitope
    • 15
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1848-1882
    Reactivité
    • 68
    • 43
    • 40
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 83
    Lapin
    Clonalité
    • 74
    • 9
    Polyclonal
    Conjugué
    • 32
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WNK1 est non-conjugé
    Application
    • 28
    • 28
    • 20
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This WNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1848-1882 amino acids from human WNK1.
    Clone
    RB56242
    Isotype
    IgG
    Top Product
    Discover our top product WNK1 Anticorps primaire
  • Indications d'application
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
    Autre désignation
    WNK1 (WNK1 Produits)
    Sujet
    Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide- sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
    Poids moléculaire
    250794
    UniProt
    Q9H4A3
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