WNK1 anticorps (AA 1848-1882)
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- Antigène Voir toutes WNK1 Anticorps
- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
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Épitope
- AA 1848-1882
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WNK1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This WNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1848-1882 amino acids from human WNK1.
- Clone
- RB56242
- Isotype
- IgG
- Top Product
- Discover our top product WNK1 Anticorps primaire
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- Indications d'application
- WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
- Autre désignation
- WNK1 (WNK1 Produits)
- Sujet
- Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide- sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
- Poids moléculaire
- 250794
- UniProt
- Q9H4A3
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