This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This APLP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the human region of human APLP1.
anticorps aplp, anticorps MGC115336, anticorps APLP, anticorps Aplp1_retired, anticorps RGD1561211, anticorps amyloid beta precursor like protein 1, anticorps amyloid beta precursor like protein 1 L homeolog, anticorps amyloid beta (A4) precursor-like protein 1, anticorps APLP1, anticorps aplp1.L, anticorps aplp1, anticorps Aplp1
Sujet
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.