BIRC6 anticorps (AA 4810-4844)

N° du produit ABIN6243063

Détail du produit anti-BIRC6 anticorps

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Épitope: AA 4810-4844

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.

Clone: RB56699

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur BIRC6

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Autre désignation: BIRC6 (BIRC6 Produits)

Synonymes: anticorps APOLLON, anticorps BRUCE, anticorps bruce, anticorps apollon, anticorps BIRC6, anticorps A430032G04Rik, anticorps A430040A19Rik, anticorps AA501170, anticorps Bruce, anticorps D630005A10Rik, anticorps mKIAA1289, anticorps baculoviral IAP repeat containing 6, anticorps baculoviral IAP repeat-containing 6, anticorps BIRC6, anticorps Birc6, anticorps birc6

Sujet: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

Poids moléculaire: 530255

UniProt: Q9NR09