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MME anticorps (AA 472-505)

Name: MME anticorps (AA 472-505)
SKU: ABIN6243087
Price: 467.5 EUR
Availability: InStock

MME Reactivité: Humain FACS, WB, IHC (p) Hôte: Souris Monoclonal 965CT9-1-1 unconjugated

All lanes : Anti-E Antibody (Center) at 1:4000 dilution Lane 1: Human placenta lysate Lane 2: Ramos whole cell lysate Lane 3: Human kidney lysate Lysates/proteins at 20 μg per lane. (MME anticorps (AA 472-505))

Immunohistochemical analysis of paraffin-embedded human kidney tissue using (ABIN6243087 and ABIN6577253) performed on the Leica® BOND RXm. (MME anticorps (AA 472-505))

IHC (p)

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 (ABIN6243087 and ABIN6577253). (MME anticorps (AA 472-505))

IHC

Overlay histogram showing Jurkat cells stained with (ABIN6243087 and ABIN6577253)(green line). (MME anticorps (AA 472-505))

FACS

4 images

N° du produit ABIN6243087

Fiche de données

Antigène Voir toutes MME Anticorps

MME (Membrane Metallo-Endopeptidase (MME))
Épitope
10

9

8

8

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 472-505
Reactivité
193

44

37

3

2

2

2

2

2

1

1

1

1
Humain
Hôte
107

91

2
Souris
Anticorps secondaires appropriés
Clonalité
117

82

2
Monoclonal
Conjugué
113

18

16

11

7

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MME est non-conjugé
Application
106

80

74

61

41

30

20

18

10

8

5

5

4

3

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène

This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.

Clone

965CT9-1-1

Isotype

IgG1 kappa

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:4000. IHC: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Date de péremption

6 months
Antigène

MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation

MME (MME Produits)

Classe de substances

Chemical

Sujet

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675, PubMed:< a href="http://www.uniprot.org/citations/8168535" target="_blank">8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:< a href="http://www.uniprot.org/citations/17101991" target="_blank">17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:< a href="http://www.uniprot.org/citations/2531377" target="_blank">2531377, PubMed:< a href="http://www.uniprot.org/citations/2972276" target="_blank">2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:< a href="http://www.uniprot.org/citations/20876573" target="_blank">20876573).

Poids moléculaire

85514

UniProt

P08473

Pathways

Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration