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COPS7B anticorps (AA 223-257)

COPS7B Reactivité: Humain WB Hôte: Lapin Polyclonal RB56231 unconjugated
N° du produit ABIN6243118
  • Antigène Voir toutes COPS7B Anticorps
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Épitope
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 223-257
    Reactivité
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPS7B est non-conjugé
    Application
    • 22
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This COPS7B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 223-257 amino acids from the Central region of human COPS7B.
    Clone
    RB56231
    Isotype
    Ig Fraction
    Top Product
    Discover our top product COPS7B Anticorps primaire
  • Indications d'application
    WB: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Autre désignation
    COPS7B (COPS7B Produits)
    Synonymes
    anticorps MGC114836, anticorps D1Wsu66e, anticorps E130114M23, anticorps CSN7B, anticorps COP9 signalosome subunit 7B, anticorps COP9 signalosome subunit 7B S homeolog, anticorps Cops7b, anticorps COPS7B, anticorps cops7b.S
    Sujet
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
    Poids moléculaire
    29622
    UniProt
    Q9H9Q2
    Pathways
    Cycle Cellulaire
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