LMCD1 anticorps (C-Term)

N° du produit ABIN6243246

Détail du produit anti-LMCD1 anticorps

Antigène: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Épitope: AA 316-350, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMCD1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.

Clone: RB40473

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur LMCD1

Antigène: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Autre désignation: LMCD1 (LMCD1 Produits)

Synonymes: anticorps LMCD1, anticorps AW455500, anticorps AW553074, anticorps dyxin, anticorps LIM and cysteine rich domains 1, anticorps LIM and cysteine-rich domains 1, anticorps LMCD1, anticorps lmcd1, anticorps Lmcd1

Sujet: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Poids moléculaire: 40833

UniProt: Q9NZU5