Znf423 anticorps (AA 864-897)

N° du produit ABIN6243344

Détail du produit anti-Znf423 anticorps

Antigène: Znf423 (Zinc Finger Protein 423 (Znf423))

Épitope: AA 864-897

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Znf423 est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ZNF423 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 864-897 amino acids from the Central region of human ZNF423.

Clone: RB49865

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Znf423

Antigène: Znf423 (Zinc Finger Protein 423 (Znf423))

Autre désignation: ZNF423 (Znf423 Produits)

Synonymes: anticorps Ebfaz, anticorps Roaz, anticorps Zfp104, anticorps Znf423, anticorps ataxia1, anticorps mKIAA0760, anticorps nur12, anticorps si:ch211-212o1.3, anticorps wu:fc95d03, anticorps ebfaz, anticorps oaz, anticorps roaz, anticorps zfp104, anticorps zfp423, anticorps JBTS19, anticorps NPHP14, anticorps OAZ, anticorps ZFP423, anticorps zgc:158272, anticorps znf423, anticorps zinc finger protein 423, anticorps zinc finger protein 423 L homeolog, anticorps si:ch211-216l23.1, anticorps Zfp423, anticorps znf423, anticorps znf423.L, anticorps ZNF423, anticorps si:ch211-216l23.1, anticorps Znf423

Sujet: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Poids moléculaire: 144605

UniProt: Q2M1K9