This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A.
Clone
RB54170
Isotype
Ig Fraction
Indications d'application
WB: 1:1000-1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.