ADAM15 anticorps (AA 37-72)

N° du produit ABIN6243467

Détail du produit anti-ADAM15 anticorps

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Épitope: AA 37-72

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM15 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ADAM15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-72 amino acids of human ADAM15.

Clone: RB52706

Isotype: IgG

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur ADAM15

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Autre désignation: ADAM15 (ADAM15 Produits)

Synonymes: anticorps ADAM15, anticorps mdc15, anticorps MDC15, anticorps metargidin, anticorps tMDCVI, anticorps ADAM metallopeptidase domain 15, anticorps ADAM metallopeptidase domain 15 L homeolog, anticorps a disintegrin and metallopeptidase domain 15 (metargidin), anticorps ADAM15, anticorps adam15.L, anticorps adam15, anticorps Adam15

Sujet: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

Poids moléculaire: 92959

UniProt: Q13444