ITGA7 anticorps (C-Term)
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- Antigène Voir toutes ITGA7 Anticorps
- ITGA7 (Integrin, alpha 7 (ITGA7))
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Épitope
- AA 1149-1181, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ITGA7 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.
- Clone
- RB52832
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ITGA7 Anticorps primaire
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- Indications d'application
- WB: 1:8000. WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." dans: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).
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Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." dans: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).
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- Antigène
- ITGA7 (Integrin, alpha 7 (ITGA7))
- Autre désignation
- ITGA7 (ITGA7 Produits)
- Sujet
- Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
- Poids moléculaire
- 128948
- UniProt
- Q13683
- Pathways
- Integrin Complex
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