GRF2 anticorps (AA 536-569)

N° du produit ABIN6243613

Détail du produit anti-GRF2 anticorps

Antigène: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Épitope: AA 536-569

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRF2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAPGEF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 536-569 amino acids from the Central region of human RAPGEF1.

Clone: RB52924

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000-1:2000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur GRF2

Antigène: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Autre désignation: RAPGEF1 (RAPGEF1 Produits)

Synonymes: anticorps C3G, anticorps GRF2, anticorps Link-GEFII, anticorps 4932418O06Rik, anticorps Grf2, anticorps RAPGEF1, anticorps C3G-1, anticorps C3G-2, anticorps C3g, anticorps rapgef1, anticorps zgc:56372, anticorps Rap guanine nucleotide exchange factor 1, anticorps Rap guanine nucleotide exchange factor like 1, anticorps Rap guanine nucleotide exchange factor (GEF) 1, anticorps Rap guanine nucleotide exchange factor 1 S homeolog, anticorps Rap guanine nucleotide exchange factor (GEF) 1b, anticorps RAPGEF1, anticorps RAPGEFL1, anticorps Rapgef1, anticorps rapgef1.S, anticorps rapgef1, anticorps rapgef1b, anticorps Rapgefl1

Sujet: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Poids moléculaire: 120548

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor