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EPH Receptor B1 anticorps (AA 304-339)

EPHB1 Reactivité: Souris, Rat WB Hôte: Lapin Polyclonal RB50839 unconjugated
N° du produit ABIN6243651
  • Antigène Voir toutes EPH Receptor B1 (EPHB1) Anticorps
    EPH Receptor B1 (EPHB1)
    Épitope
    • 22
    • 15
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 304-339
    Reactivité
    • 57
    • 47
    • 41
    • 1
    Souris, Rat
    Hôte
    • 64
    • 4
    • 4
    Lapin
    Clonalité
    • 70
    • 2
    Polyclonal
    Conjugué
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPH Receptor B1 est non-conjugé
    Application
    • 62
    • 27
    • 27
    • 27
    • 13
    • 12
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    H
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Mouse Ephb1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 304-339 amino acids from the Central region of Mouse Ephb1.
    Clone
    RB50839
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EPHB1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    EPH Receptor B1 (EPHB1)
    Autre désignation
    Ephb1 (EPHB1 Produits)
    Synonymes
    anticorps ELK, anticorps EPHT2, anticorps Hek6, anticorps NET, anticorps ephb1-a, anticorps xek, anticorps Xek, anticorps MGC89790, anticorps EPHB1, anticorps CEK6, anticorps EK6, anticorps 9330129L11, anticorps AW488255, anticorps C130099E04Rik, anticorps Cek6, anticorps ENSMUSG00000074119, anticorps Elk, anticorps Elkh, anticorps Net, anticorps Ephb2, anticorps Erk, anticorps elk, anticorps EPH receptor B1, anticorps EPH receptor B1 S homeolog, anticorps ephrin type-B receptor 1, anticorps Eph receptor B1, anticorps EPHB1, anticorps ephb1.S, anticorps ephb1, anticorps LOC100467687, anticorps Ephb1
    Sujet
    Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
    Poids moléculaire
    109881
    UniProt
    Q8CBF3
    Pathways
    Signalisation RTK
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