KANK2 anticorps (AA 343-376)

N° du produit ABIN6243798

Détail du produit anti-KANK2 anticorps

Antigène: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Épitope: AA 343-376

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KANK2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KANK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-376 amino acids from the Central region of human KANK2.

Clone: RB48827

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur KANK2

Antigène: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Autre désignation: KANK2 (KANK2 Produits)

Synonymes: anticorps ANKRD25, anticorps MXRA3, anticorps SIP, anticorps AI504612, anticorps Ankrd25, anticorps BC010245, anticorps KN motif and ankyrin repeat domains 2, anticorps KANK2, anticorps Kank2

Sujet: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:< a href="http://www.uniprot.org/citations/24671081" target="_blank">24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:< a href="http://www.uniprot.org/citations/22371500" target="_blank">22371500). May be involved in promotion of cell proliferation (By similarity).

Poids moléculaire: 91174

UniProt: Q63ZY3