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MAD2L2 anticorps (C-Term)

MAD2L2 Reactivité: Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB48484 unconjugated
N° du produit ABIN6243877
  • Antigène Voir toutes MAD2L2 Anticorps
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Épitope
    • 15
    • 9
    • 4
    • 1
    • 1
    • 1
    AA 198-231, C-Term
    Reactivité
    • 42
    • 12
    • 11
    • 1
    Souris
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 32
    • 11
    Polyclonal
    Conjugué
    • 18
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAD2L2 est non-conjugé
    Application
    • 31
    • 14
    • 14
    • 13
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2.
    Clone
    RB48484
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAD2L2 Anticorps primaire
  • Indications d'application
    IF: 1:25. WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Autre désignation
    MAD2L2 (MAD2L2 Produits)
    Synonymes
    anticorps mad2b, anticorps 2310033C13Rik, anticorps MAD2B, anticorps REV7, anticorps mad2B, anticorps mad2l2-A, anticorps xMAD2L2, anticorps POLZ2, anticorps mad2l2, anticorps zgc:110299, anticorps mitotic arrest deficient 2 like 2, anticorps MAD2 mitotic arrest deficient-like 2, anticorps mitotic arrest deficient 2 like 2 S homeolog, anticorps MAD2 mitotic arrest deficient-like 2 (yeast), anticorps si:dkey-23c22.2, anticorps mad2l2, anticorps MAD2L2, anticorps Mad2l2, anticorps mad2l2.S, anticorps si:dkey-23c22.2
    Sujet
    Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
    Poids moléculaire
    24334
    UniProt
    Q9UI95
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