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SNW1 anticorps (AA 464-497)

SNW1 Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal RB54232 unconjugated
N° du produit ABIN6243922
  • Antigène Voir toutes SNW1 Anticorps
    SNW1 (SNW Domain Containing 1 (SNW1))
    Épitope
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 464-497
    Reactivité
    • 14
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 14
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 14
    Cet anticorp SNW1 est non-conjugé
    Application
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SNW1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from human SNW1.
    Clone
    RB54232
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SNW1 Anticorps primaire
  • Indications d'application
    IF: 1:25. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    SNW1 (SNW Domain Containing 1 (SNW1))
    Autre désignation
    SNW1 (SNW1 Produits)
    Synonymes
    anticorps Gle1l1, anticorps Skiip, anticorps bx42, anticorps ncoa-62, anticorps prp45, anticorps prpf45, anticorps skiip, anticorps skip, anticorps Bx42, anticorps NCOA-62, anticorps PRPF45, anticorps Prp45, anticorps SKIIP, anticorps SKIP, anticorps 2310008B08Rik, anticorps AW048543, anticorps NCoA-62, anticorps SNW domain containing 1, anticorps nuclear protein SkiP, anticorps puff-specific protein Bx42, anticorps putative nuclear protein SkiP, anticorps GLE1 RNA export mediator homolog (yeast), pseudogene 1, anticorps SNW domain containing 1 S homeolog, anticorps snw1, anticorps PVX_002605, anticorps LOC5564605, anticorps Smp_105860, anticorps UREG_03916, anticorps Gle1-ps1, anticorps snw1.S, anticorps SNW1, anticorps Snw1
    Sujet
    Involved in transcriptional regulation. Modulates TGF- beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1- mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA, the function probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
    Poids moléculaire
    61494
    UniProt
    Q13573
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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