ROS1 anticorps
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- Antigène Voir toutes ROS1 Anticorps
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ROS1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogène
- This ROS1 antibody is generated from a mouse immunized with a recombinant protein of human ROS1.
- Clone
- 1843CT776-78-21
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ROS1 Anticorps primaire
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- Indications d'application
- IHC: 1:250. WB: 1:4000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Autre désignation
- ROS1 (ROS1 Produits)
- Sujet
- Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
- Poids moléculaire
- 263915
- UniProt
- P08922
- Pathways
- Signalisation RTK
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