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R-Spondin 3 anticorps (AA 214-248)

RSPO3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB54573 unconjugated
N° du produit ABIN6243983
  • Antigène Voir toutes R-Spondin 3 (RSPO3) Anticorps
    R-Spondin 3 (RSPO3)
    Épitope
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-248
    Reactivité
    • 23
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 18
    • 2
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 21
    • 4
    Polyclonal
    Conjugué
    • 19
    • 2
    • 2
    • 2
    Cet anticorp R-Spondin 3 est non-conjugé
    Application
    • 18
    • 13
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This RSPO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 214-248 amino acids from human RSPO3.
    Clone
    RB54573
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RSPO3 Anticorps primaire
  • Indications d'application
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    R-Spondin 3 (RSPO3)
    Autre désignation
    RSPO3 (RSPO3 Produits)
    Synonymes
    anticorps pwtsr, anticorps thsd2, anticorps cristin1, anticorps CRISTIN1, anticorps PWTSR, anticorps THSD2, anticorps RGD1563246, anticorps 2810459H04Rik, anticorps AW742308, anticorps Cristin1, anticorps Thsd2, anticorps R-spondin 3, anticorps rspo3, anticorps RSPO3, anticorps Rspo3
    Sujet
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
    Poids moléculaire
    30929
    UniProt
    Q9BXY4
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