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RENT1/UPF1 anticorps (AA 583-612)

UPF1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB8354 unconjugated
N° du produit ABIN6243988
  • Antigène Voir toutes RENT1/UPF1 (UPF1) Anticorps
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 583-612
    Reactivité
    • 53
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 3
    • 3
    Lapin
    Clonalité
    • 46
    • 7
    Polyclonal
    Conjugué
    • 29
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RENT1/UPF1 est non-conjugé
    Application
    • 25
    • 16
    • 14
    • 14
    • 8
    • 8
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the Central region of human RENT1.
    Clone
    RB8354
    Isotype
    Ig Fraction
    Top Product
    Discover our top product UPF1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Tian, Macdonald et al.: "The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 ..." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5937-52, (2012) (PubMed).

  • Antigène
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Autre désignation
    RENT1 (UPF1 Produits)
    Sujet
    RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
    Poids moléculaire
    124345
    NCBI Accession
    NP_002902
    UniProt
    Q92900
    Pathways
    SARS-CoV-2 Protein Interactome
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