This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SPDYA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SPDYA.
anticorps zgc:101624, anticorps 4921517J08Rik, anticorps 4930548B21Rik, anticorps GS4, anticorps MLZ-465, anticorps Spdy1, anticorps RINGO, anticorps SPDY1, anticorps RINGO3, anticorps RINGOA, anticorps SPY1, anticorps Gs4, anticorps Lm23, anticorps Spy1, anticorps speedy homolog A (Xenopus laevis), anticorps speedy/RINGO cell cycle regulator family member A, anticorps speedy/RINGO cell cycle regulator family, member A, anticorps SPDYA, anticorps spdya, anticorps Spdya
Sujet
SPDYA (speedy homolog A (Drosophila)) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.