KDM1B anticorps (N-Term)

N° du produit ABIN6244065

Détail du produit anti-KDM1B anticorps

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Épitope: AA 38-73, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KDM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 38-73 amino acids from the N-terminal region of human KDM1B.

Clone: RB49895

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: KDM1B (KDM1B Produits)

Synonymes: anticorps AOF1, anticorps C6orf193, anticorps LSD2, anticorps bA204B7.3, anticorps dJ298J15.2, anticorps 4632428N09Rik, anticorps AI482520, anticorps Aof1, anticorps lysine demethylase 1B, anticorps lysine-specific histone demethylase 1B, anticorps lysine (K)-specific demethylase 1B, anticorps KDM1B, anticorps LOC577549, anticorps kdm1b, anticorps Kdm1b

Sujet: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri- methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys- 36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity).

Poids moléculaire: 92098

UniProt: Q8NB78

Pathways: L'effet Warburg