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SRGAP2 anticorps (C-Term)

SRGAP2 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB53245 unconjugated
N° du produit ABIN6244085
  • Antigène Voir toutes SRGAP2 Anticorps
    SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
    Épitope
    • 2
    • 2
    • 1
    • 1
    AA 1040-1071, C-Term
    Reactivité
    • 16
    • 11
    • 9
    Humain, Souris
    Hôte
    • 15
    • 1
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SRGAP2 est non-conjugé
    Application
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SRGAP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1040-1071amino acids from the C-terminal region of human SRGAP2.
    Clone
    RB53245
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SRGAP2 Anticorps primaire
  • Indications d'application
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
    Autre désignation
    SRGAP2 (SRGAP2 Produits)
    Synonymes
    anticorps ARHGAP34, anticorps FNBP2, anticorps SRGAP2A, anticorps SRGAP3, anticorps 9930124L22Rik, anticorps AI448945, anticorps FBP2, anticorps Fnbp2, anticorps srGAP3, anticorps AI452337, anticorps Arhgap14, anticorps D130026O08Rik, anticorps Gbi, anticorps MEGAP, anticorps WRP, anticorps mKIAA0411, anticorps RGD1566016, anticorps srGAP2, anticorps srgap2a, anticorps wu:fb47h12, anticorps zgc:136814, anticorps fnbp2, anticorps srgap2, anticorps SLIT-ROBO Rho GTPase activating protein 2, anticorps SLIT-ROBO Rho GTPase activating protein 3, anticorps SLIT-ROBO Rho GTPase activating protein 2 L homeolog, anticorps SRGAP2, anticorps Srgap2, anticorps Srgap3, anticorps srgap2, anticorps srgap2.L
    Sujet
    RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
    Poids moléculaire
    120871
    UniProt
    O75044
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