H3F3B anticorps (AA 103-136)

N° du produit ABIN6244249

Détail du produit anti-H3F3B anticorps

Antigène: H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

Épitope: AA 103-136

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H3F3B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-136 amino acids from mouse H3f3b.

Clone: RB53621

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur H3F3B

Antigène: H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

Autre désignation: H3f3b (H3F3B Produits)

Synonymes: anticorps 9430068D06Rik, anticorps H3.3B, anticorps H3 histone, family 3B, anticorps H3 histone family member 3B, anticorps H3f3b, anticorps H3F3B

Sujet: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Poids moléculaire: 15328

UniProt: P84244