Mare/Nprl3/C16orf35 anticorps (AA 86-117)

N° du produit ABIN6244303

Détail du produit anti-Mare/Nprl3/C16orf35 anticorps

Antigène: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Épitope: AA 86-117

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mare/Nprl3/C16orf35 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.

Clone: RB54296

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Mare/Nprl3/C16orf35

Antigène: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Autre désignation: NPRL3 (C16orf35 Produits)

Synonymes: anticorps C16orf35, anticorps CGTHBA, anticorps HS-40, anticorps MARE, anticorps NPR3, anticorps RMD11, anticorps Aag, anticorps HS-26, anticorps Mare, anticorps Phg, anticorps Prox1, anticorps m(alpha)RE, anticorps RGD1308665, anticorps c16orf35, anticorps cgthba, anticorps hs-40, anticorps mare, anticorps npr3, anticorps nprl3, anticorps rmd11, anticorps NPR3 like, GATOR1 complex subunit, anticorps nitrogen permease regulator-like 3, anticorps NPR3-like, GATOR1 complex subunit, anticorps NPR3-like, GATOR1 complex subunit L homeolog, anticorps NPRL3, anticorps Nprl3, anticorps nprl3.L

Sujet: As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

Poids moléculaire: 63605

UniProt: Q12980