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FAT Atypical Cadherin 2 (FAT2) anticorps

FAT2 Reactivité: Humain IF, FACS, IHC, WB Hôte: Souris Monoclonal 8C5 unconjugated
N° du produit ABIN6251792
  • Antigène Voir toutes FAT Atypical Cadherin 2 (FAT2) Anticorps
    FAT Atypical Cadherin 2 (FAT2)
    Reactivité
    • 14
    • 1
    • 1
    Humain
    Hôte
    • 9
    • 5
    Souris
    Clonalité
    • 9
    • 5
    Monoclonal
    Conjugué
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 10
    • 9
    • 9
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Protein G affinity chromatography
    Immunogène
    A recombinant human Protocadherin Fat 2 fusion protein was used as the immunogen for this FAT2 antibody.
    Clone
    8C5
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FAT2 Anticorps primaire
  • Indications d'application
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 1-2 μg/mL

    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT

    Titering of the FAT2 antibody may be required for optimal performance.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Antigène
    FAT Atypical Cadherin 2 (FAT2)
    Autre désignation
    FAT2 (FAT2 Produits)
    Synonymes
    anticorps EMI2, anticorps Fath2, anticorps Gm523, anticorps mKIAA0811, anticorps CDHF8, anticorps CDHR9, anticorps HFAT2, anticorps MEGF1, anticorps FAT atypical cadherin 2, anticorps Fat2, anticorps FAT2
    Sujet
    Recognizes a protein of 480  kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
    ID gène
    2196
    UniProt
    Q9NYQ8
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