CD45 anticorps (FITC)

N° du produit ABIN6253903

Détail du produit anti-CD45 anticorps (FITC)

Antigène: CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD45 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité: CD45 (ML2) reacts with the CD45 antigen, also known as the leukocyte common antigen (LCA) or T200 antigen, comprised of different glycoproteins ranging from 180-240 kD

Clone: ML2

Isotype: IgG1

Information d'application

Indications d'application: immunohistochemistry on frozen tissue sections, immunohistochemistry on paraffin imbedded tissue sections

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Détails sur CD45

Antigène: CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Autre désignation: CD45 (PTPRC Produits)

Synonymes: anticorps PTPRC, anticorps si:dkeyp-47c5.1, anticorps B220, anticorps CD45, anticorps CD45R, anticorps GP180, anticorps L-CA, anticorps LCA, anticorps LY5, anticorps T200, anticorps Cd45, anticorps Ly-5, anticorps Lyt-4, anticorps loc, anticorps Lca, anticorps RT7, anticorps cd45, anticorps protein tyrosine phosphatase, receptor type C, anticorps protein tyrosine phosphatase, receptor type, C, anticorps receptor-type tyrosine-protein phosphatase C, anticorps PTPRC, anticorps ptprc, anticorps LOC100074271, anticorps Ptprc

Sujet: Antigen distribution: CD44, otherwise known as the lymphocyte homing receptor, is widely expressed on hematopoietic and non-hematopoietic cells. It is found especially on epithelial, endothelial, mesothelial and mesenchymal cells as well as in the nervous system. The major isoform is CD44H which is expressed on lymphoid, myeloid and erythroid cells. Expression is increased on activated and memory/effector T cells. Soluble forms of CD44 can be detected in body fluids [1,2]. MEM-85 was clustered at the Leukocyte Typing Workshop IV [3,4]. Cellular Expression: Pan leukocytes (RA, RB, RO isoforms).

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling