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VCAM1 anticorps (FITC)

VCAM1 Reactivité: Humain FACS, ICC Hôte: Souris Monoclonal B-K9 FITC
N° du produit ABIN6253936
  • Antigène Voir toutes VCAM1 Anticorps
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reactivité
    • 112
    • 77
    • 28
    • 11
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 76
    • 64
    • 43
    • 5
    • 1
    • 1
    Souris
    Clonalité
    • 125
    • 63
    • 1
    Monoclonal
    Conjugué
    • 89
    • 27
    • 24
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VCAM1 est conjugé à/à la FITC
    Application
    • 90
    • 77
    • 57
    • 40
    • 36
    • 27
    • 19
    • 16
    • 14
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificité
    B-K9 produces mouse IgG1 immunoglobulins directed against a 110 kD protein known as human CD106. It reacts with approximately 15% of peripheral lymphocytes and between 30-90% activated HUVEC
    Clone
    B-K9
    Isotype
    IgG1
    Top Product
    Discover our top product VCAM1 Anticorps primaire
  • Indications d'application
    tochemistry on cytospots,  immunohistochemistry on frozen tissue sections
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C
  • Antigène
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Autre désignation
    CD106 (VCAM1 Produits)
    Synonymes
    anticorps CD106, anticorps INCAM-100, anticorps Vcam-1, anticorps VCAM1B, anticorps fi76d06, anticorps wu:fi76d06, anticorps zgc:158875, anticorps VCAM1, anticorps vascular cell adhesion molecule 1, anticorps vascular cell adhesion molecule 1b, anticorps VCAM1, anticorps Vcam1, anticorps vcam1b, anticorps VCAM-1
    Sujet
    Antigen distribution: CD106 antigen binds the integrins a4b1 (CD49d/CD29, VLA-4) and a4b7 [4]. VLA-4 is the dominant ligand in cells expressing both integrins. Endothelial CD106 contributes to the extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, especially at sites of inflammation. The VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion [5]. CD106 expression on non-vascular tissues is thought to play a role in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, co-stimulation of T cells and embryonic development [1,2,3]. Cellular Expression: VCAM-1. Vascular endothelium, dendritic cells, macrophages
    Pathways
    Carbohydrate Homeostasis
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