FMR1 anticorps (pSer499)

N° du produit ABIN6254033

Détail du produit anti-FMR1 anticorps

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Épitope: pSer499

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FMR1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus)

Homologie: bovine, canine, chicken, human, mouse, non-human primates, sheep, Xenopus, zebra fish

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser499 conjugated to KLH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Références pour anticorps anti-FMR1 (ABIN6254033)

Bartley, OKeefe, Blice-Baum, Mihailescu, Gong, Miyares, Karaca, Bordey: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." dans: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).

Reynolds, Smith, Jefferson, Lugo: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).

Guimarães-Souza, Perche, Morgans, Duvoisin, Calaza: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." dans: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).

Bartley, OKeefe, Bordey: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." dans: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).

Détails sur FMR1

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Autre désignation: FMR1 (FMR1 Produits)

Synonymes: anticorps AT24755, anticorps BcDNA:GM08679, anticorps CG6203, anticorps Dmel\\CG6203, anticorps EP(3)3517, anticorps FMR, anticorps FMR1, anticorps FMRP, anticorps FMRp, anticorps FXR, anticorps Fmrp, anticorps cg6203, anticorps dFMR, anticorps dFMR1, anticorps dFMRP, anticorps dFXR, anticorps dFXR1, anticorps dFXRP, anticorps dFmr1, anticorps dFmrp, anticorps dfmr, anticorps dfmr1, anticorps dfxr, anticorps dfxr1, anticorps dmfr1, anticorps fmr, anticorps fmr1, anticorps FRAXA, anticorps POF, anticorps POF1, anticorps zFMR1, anticorps Fmr-1, anticorps CG6203 gene product from transcript CG6203-RC, anticorps fragile X mental retardation 1, anticorps fragile X mental retardation syndrome 1, anticorps Fmr1, anticorps FMR1, anticorps fmr1

Poids moléculaire: '71 kDa

ID gène: 24948

UniProt: Q80WE1

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development