NME1 anticorps (C-Term)

N° du produit ABIN6254892

Détail du produit anti-NME1 anticorps

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: NME1 Antibody detects endogenous levels of total NME1.

Homologie: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NME1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NME1

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Autre désignation: NME1 (NME1 Produits)

Synonymes: anticorps AWD, anticorps GAAD, anticorps NB, anticorps NBS, anticorps NDKA, anticorps NDPK-A, anticorps NDPKA, anticorps NM23, anticorps NM23-H1, anticorps AL024257, anticorps NM23-M1, anticorps NM23A, anticorps NDPK-Z1, anticorps NM23-B, anticorps NM23-Z1, anticorps ndpkz1, anticorps nm23b, anticorps nme1, anticorps nme2, anticorps nme2b1, anticorps NME1, anticorps NME1-NME2, anticorps NM23-C1, anticorps ndpk-b, anticorps ndpkb, anticorps nm23-h2, anticorps nm23ndk, anticorps puf, anticorps NBR-A, anticorps NBR-B, anticorps NME1-1, anticorps nm23ndk-a, anticorps NDK I, anticorps NDPK I, anticorps T30A10.80, anticorps T30A10_80, anticorps NDP kinase I, anticorps NME/NM23 nucleoside diphosphate kinase 1, anticorps NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1, anticorps non-metastatic cells 1, protein (NM23A) expressed in, anticorps NME/NM23 nucleoside diphosphate kinase 2 S homeolog, anticorps NME/NM23 nucleoside diphosphate kinase 2 L homeolog, anticorps nucleoside diphosphate kinase, anticorps nucleoside diphosphate kinase 1, anticorps NME1, anticorps Nme1, anticorps nme2b.1, anticorps nme2.S, anticorps nme2.L, anticorps LOC547870, anticorps NDPK1, anticorps LOC107790563

Sujet:

Description: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

Gene: NME1

Poids moléculaire: 17kDa

ID gène: 4830

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process