FOXO4 anticorps (pSer197)
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- Antigène Voir toutes FOXO4 Anticorps
- FOXO4 (Forkhead Box O4 (FOXO4))
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Épitope
- pSer197
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXO4 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Phospho-FOXO4 (Ser197) Antibody detects endogenous levels of FOXO4 only when phosphorylated at Serine 197.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogène
- A synthesized peptide derived from human FOXO4 around the phosphorylation site of Ser197.
- Isotype
- IgG
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- FOXO4 (Forkhead Box O4 (FOXO4))
- Autre désignation
- FOXO4 (FOXO4 Produits)
- Synonymes
- anticorps FOXO4, anticorps foxo4, anticorps AFX, anticorps AFX1, anticorps MLLT7, anticorps Afxh, anticorps Mllt7, anticorps afx, anticorps RGD1561201, anticorps forkhead box O4, anticorps forkhead box O4 L homeolog, anticorps FOXO4, anticorps foxo4.L, anticorps Foxo4
- Sujet
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Description: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Gene: FOXO4
- Poids moléculaire
- 65kDa
- ID gène
- 4303
- UniProt
- P98177
- Pathways
- Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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