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FOXO4 anticorps (pSer197)

FOXO4 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6255069
  • Antigène Voir toutes FOXO4 Anticorps
    FOXO4 (Forkhead Box O4 (FOXO4))
    Épitope
    • 26
    • 18
    • 14
    • 10
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer197
    Reactivité
    • 143
    • 70
    • 63
    • 10
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 141
    • 1
    • 1
    Lapin
    Clonalité
    • 133
    • 10
    Polyclonal
    Conjugué
    • 65
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Cet anticorp FOXO4 est non-conjugé
    Application
    • 106
    • 51
    • 39
    • 39
    • 24
    • 17
    • 16
    • 9
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Phospho-FOXO4 (Ser197) Antibody detects endogenous levels of FOXO4 only when phosphorylated at Serine 197.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human FOXO4 around the phosphorylation site of Ser197.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    FOXO4 (Forkhead Box O4 (FOXO4))
    Autre désignation
    FOXO4 (FOXO4 Produits)
    Synonymes
    anticorps FOXO4, anticorps foxo4, anticorps AFX, anticorps AFX1, anticorps MLLT7, anticorps Afxh, anticorps Mllt7, anticorps afx, anticorps RGD1561201, anticorps forkhead box O4, anticorps forkhead box O4 L homeolog, anticorps FOXO4, anticorps foxo4.L, anticorps Foxo4
    Sujet

    Description: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

    Gene: FOXO4

    Poids moléculaire
    65kDa
    ID gène
    4303
    UniProt
    P98177
    Pathways
    Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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