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EIF4E anticorps (pSer209)

EIF4E Reactivité: Humain, Rat, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6255087
  • Antigène Voir toutes EIF4E Anticorps
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Épitope
    • 37
    • 15
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer209
    Reactivité
    • 121
    • 62
    • 50
    • 19
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 104
    • 17
    • 1
    Lapin
    Clonalité
    • 96
    • 26
    Polyclonal
    Conjugué
    • 55
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp EIF4E est non-conjugé
    Application
    • 94
    • 48
    • 38
    • 27
    • 27
    • 26
    • 16
    • 14
    • 14
    • 12
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Phospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at Serine 209.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human eIF4E around the phosphorylation site of Ser209.
    Isotype
    IgG
    Top Product
    Discover our top product EIF4E Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Autre désignation
    EIF4E (EIF4E Produits)
    Sujet

    Description: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

    Gene: EIF4E

    Poids moléculaire
    25kDa
    ID gène
    1977
    UniProt
    P06730
    Pathways
    BCR Signaling
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