Cofilin anticorps (pSer3)

N° du produit ABIN6255180

Détail du produit anti-Cofilin anticorps

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Épitope: pSer3

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Phospho-Cofilin (Ser3) Antibody detects endogenous levels of Cofilin only when phosphorylated at Serine 3.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Cofilin around the phosphorylation site of Ser3.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Cofilin

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation: CFL1 (CFL1 Produits)

Synonymes: anticorps cfl1, anticorps xac1, anticorps xac2, anticorps cfl, anticorps cb86, anticorps sb:cb86, anticorps zgc:56501, anticorps wu:fb18a04, anticorps wu:fk77b03, anticorps 12/8, anticorps ADF, anticorps ADF/cofilin, anticorps Adf, anticorps CG4254, anticorps Cadf, anticorps D-cof, anticorps D61, anticorps Dmel\\CG4254, anticorps T8, anticorps Tsr, anticorps cofilin, anticorps cofilin/ADF, anticorps cofilin/actin depolymerizing factor homolog, anticorps l(2)03101, anticorps l(2)k03101, anticorps l(2)k05633, anticorps l(2)k13409, anticorps ntf, anticorps CFL, anticorps AA959946, anticorps Cof, anticorps CFL1, anticorps cofilin 1 (non-muscle) L homeolog, anticorps cofilin 1 (non-muscle), anticorps cofilin 1 (non-muscle), like, anticorps cofilin 1, anticorps twinstar, anticorps cofilin, anticorps cofilin 1, non-muscle, anticorps Contrafreeloading, anticorps cfl1.L, anticorps cfl1, anticorps cfl1l, anticorps CFL1, anticorps tsr, anticorps COF1, anticorps TSTA_042790, anticorps Cfl1, anticorps CFL

Sujet:

Description: Binds to F-actin and exhibits  pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).

Gene: CFL1

Poids moléculaire: 19kDa

ID gène: 1072

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events