NRF2 anticorps (pSer40)
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- Antigène Voir toutes NRF2 (NFE2L2) Anticorps
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Épitope
- pSer40
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NRF2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Phospho-Nrf2 (Ser40) Antibody detects endogenous levels of Nrf2 only when phosphorylated at S40.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Chicken
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogène
- A synthesized peptide derived from human nrf2 around the phosphorylation site of Ser40.
- Isotype
- IgG
- Top Product
- Discover our top product NFE2L2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Autre désignation
- NFE2L2 (NFE2L2 Produits)
- Sujet
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Description: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Gene: NFE2L2
- Poids moléculaire
- 90 kDa
- ID gène
- 4780
- UniProt
- Q16236
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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