SREBF1 anticorps (pSer439)

N° du produit ABIN6255339

Détail du produit anti-SREBF1 anticorps

Antigène: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Épitope: pSer439

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SREBF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Phospho-SREBP1 (Ser439) Antibody detects endogenous levels of SREBP1 only when phosphorylated at Serine 439.

Homologie: Pig,Horse,Sheep,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human SREBP1 around the phosphorylation site of Ser439.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SREBF1

Antigène: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Autre désignation: SREBF1 (SREBF1 Produits)

Synonymes: anticorps SREBP-1c, anticorps SREBP1, anticorps bHLHd1, anticorps ADD-1, anticorps ADD1, anticorps D630008H06, anticorps SREBP-1, anticorps SREBP-1a, anticorps SREBP1c, anticorps Srebp1, anticorps SCREBP1, anticorps SREBP-1C, anticorps SREBF1, anticorps srebp1, anticorps sterol regulatory element binding transcription factor 1, anticorps sterol regulatory element binding transcription factor 1 L homeolog, anticorps sterol regulatory element binding protein-1, anticorps Sterol regulatory element Binding Protein, anticorps SREBF1, anticorps Srebf1, anticorps srebf1.L, anticorps SREBP-1, anticorps srebf1, anticorps sbp-1

Sujet:

Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').

Gene: SREBF1

Poids moléculaire: 122kDa

ID gène: 6720

UniProt: P36956

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha