Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

IRS1 anticorps (pSer636)

IRS1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6255436
  • Antigène Voir toutes IRS1 Anticorps
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    Épitope
    • 32
    • 29
    • 27
    • 27
    • 25
    • 21
    • 18
    • 17
    • 16
    • 16
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer636
    Reactivité
    • 317
    • 255
    • 231
    • 24
    • 18
    • 18
    • 17
    • 16
    • 16
    • 15
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 314
    • 16
    Lapin
    Clonalité
    • 308
    • 22
    Polyclonal
    Conjugué
    • 138
    • 14
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    Cet anticorp IRS1 est non-conjugé
    Application
    • 171
    • 126
    • 104
    • 92
    • 91
    • 65
    • 61
    • 49
    • 24
    • 18
    • 11
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Phospho-IRS-1 (Ser636) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 636
     Réactivité croisée
    Humain, Singe, Souris, Rat (Rattus)
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 636
    Isotype
    IgG
    Top Product
    Discover our top product IRS1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    Autre désignation
    IRS-1 (IRS1 Produits)
    Synonymes
    anticorps HIRS-1, anticorps G972R, anticorps IRS-1, anticorps IRS1IRM, anticorps irs1, anticorps irsu, anticorps IRS1, anticorps irs-1, anticorps irs1-a, anticorps insulin receptor substrate 1, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 1 S homeolog, anticorps IRS1, anticorps Irs1, anticorps irs2, anticorps irs1.S
    Sujet

    Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

    Gene: IRS1

    Poids moléculaire
    180kDa
    ID gène
    3667
    UniProt
    P35568
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Vous êtes ici:
Support technique