Caldesmon anticorps (pSer789)

N° du produit ABIN6255507

Détail du produit anti-Caldesmon anticorps

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Épitope: pSer789

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caldesmon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Phospho-Caldesmon (Ser789) Antibody detects endogenous levels of Caldesmon only when phosphorylated at Serine 789.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Caldesmon

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Autre désignation: CALD1 (CALD1 Produits)

Synonymes: anticorps CDM, anticorps H-CAD, anticorps HCAD, anticorps L-CAD, anticorps LCAD, anticorps NAG22, anticorps l-Cad, anticorps 4833423D12Rik, anticorps AI195384, anticorps AV071549, anticorps AW536160, anticorps C920027I18Rik, anticorps CALD1, anticorps Caldesmon, anticorps caldesmon 1, anticorps CALD1, anticorps Cald1

Sujet:

Description: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).

Gene: CALD1

Poids moléculaire: 80kDa

ID gène: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction