FRS2 anticorps (pTyr436)

N° du produit ABIN6255918

Détail du produit anti-FRS2 anticorps

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Épitope: pTyr436

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FRS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: Phospho-FRS2 (Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyrosine 436.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur FRS2

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Autre désignation: FRS2 (FRS2 Produits)

Synonymes: anticorps frs2, anticorps wu:fd21h10, anticorps zgc:91973, anticorps FRS2A, anticorps FRS2alpha, anticorps SNT, anticorps SNT-1, anticorps SNT1, anticorps 4732458E18, anticorps C330018A15Rik, anticorps Frs2alpha, anticorps fibroblast growth factor receptor substrate 2, anticorps fibroblast growth factor receptor substrate 2b, anticorps FRS2, anticorps frs2b, anticorps Frs2

Sujet:

Description: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Gene: FRS2

Poids moléculaire: 65kDa

ID gène: 10818

UniProt: Q8WU20

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2