PDCD4 anticorps (pSer457)

N° du produit ABIN6256345

Détail du produit anti-PDCD4 anticorps

Antigène: PDCD4 (Programmed Cell Death 4 (PDCD4))

Épitope: pSer457

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCD4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Phospho-PDCD4 (Ser457) Antibody detects endogenous levels of PDCD4 only when phosphorylated at Serine 457.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser457.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PDCD4

Antigène: PDCD4 (Programmed Cell Death 4 (PDCD4))

Autre désignation: PDCD4 (PDCD4 Produits)

Synonymes: anticorps H731, anticorps D19Ucla1, anticorps Ma3, anticorps Tis, anticorps Dug, anticorps cb45, anticorps pdcd4, anticorps sb:cb45, anticorps wu:fc84b08, anticorps h731, anticorps MGC69337, anticorps PDCD4, anticorps wu:fa55g03, anticorps wu:fb08a11, anticorps wu:fe01a02, anticorps zgc:66311, anticorps programmed cell death 4, anticorps programmed cell death 4b, anticorps programmed cell death 4 L homeolog, anticorps programmed cell death 4 (neoplastic transformation inhibitor), anticorps programmed cell death 4a, anticorps PDCD4, anticorps Pdcd4, anticorps pdcd4b, anticorps pdcd4.L, anticorps pdcd4, anticorps pdcd4a

Sujet:

Description: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Gene: PDCD4

Poids moléculaire: 51kDa

ID gène: 27250

UniProt: Q53EL6