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c-MYC anticorps (pThr58)

MYC Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6256584
  • Antigène Voir toutes c-MYC (MYC) Anticorps
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Épitope
    • 59
    • 47
    • 44
    • 41
    • 24
    • 22
    • 17
    • 15
    • 15
    • 13
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr58
    Reactivité
    • 357
    • 161
    • 113
    • 15
    • 15
    • 13
    • 13
    • 13
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 274
    • 101
    • 7
    • 5
    • 3
    • 1
    Lapin
    Clonalité
    • 270
    • 120
    Polyclonal
    Conjugué
    • 188
    • 31
    • 25
    • 23
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp c-MYC est non-conjugé
    Application
    • 284
    • 135
    • 92
    • 82
    • 74
    • 58
    • 55
    • 28
    • 26
    • 20
    • 18
    • 14
    • 12
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificité
    Phospho-c-Myc (Thr58) Antibody detects endogenous levels of c-Myc only when phosphorylated at Threonine 58.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human c-Myc around the phosphorylation site of Thr58.
    Isotype
    IgG
    Top Product
    Discover our top product MYC Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Autre désignation
    MYC (MYC Produits)
    Sujet

    Description: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).

    Gene: MYC

    Poids moléculaire
    57kDa
    ID gène
    4609
    UniProt
    P01106
    Pathways
    Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg
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